Analysis of Folate by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry 


Vol. 24,  No. 9, pp. 1308-0, Sep.  2003
10.5012/bkcs.2003.24.9.1308


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  Abstract

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used to observe folic acid and its derivatives such as tetrahydrofolate and 5-methyltetrahydrofolate in a vitamin tablet and in foods. Folic acid in a vitamin tablet was determined using angiotensin I as an internal reference. Tetrahydrofolic acid, 5-methyltetrahydrofolic acid, and an oxygenated folate were observed from a human blood sample using graphite plate. The results show that these mass spectrometric methods are useful for quickly obtaining a profile of folates.

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  Cite this article

[IEEE Style]

S. Cha and H. Kim, "Analysis of Folate by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry," Bulletin of the Korean Chemical Society, vol. 24, no. 9, pp. 1308-0, 2003. DOI: 10.5012/bkcs.2003.24.9.1308.

[ACM Style]

Sangwon Cha and Hie-Joon Kim. 2003. Analysis of Folate by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Bulletin of the Korean Chemical Society, 24, 9, (2003), 1308-0. DOI: 10.5012/bkcs.2003.24.9.1308.

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ISSN(Print) 0253-2964
ISSN(Online) 1229-5949