A New Approach to the Synthesis of Optically Active Norephedrine, Norpseudoephedrine and Cathinone via Double Asymmetric Induction 


Vol. 24,  No. 11, pp. 1641-0, Nov.  2003
10.5012/bkcs.2003.24.11.1641


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  Abstract

New and facile synthetic routes for preparation of optically active norephedrine, norpseudoephedrine and cathinone with high optical purities via double asymmetric induction by employing asymmetric reduction of 2-N-protected amino (or azido)-1-phenylpropanone and 2-methanesulfonyloxy-1-phenylpropanone with CBScatalyzed-borane and dIpc2BCl as chiral reducing agents are described.

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  Cite this article

[IEEE Style]

D. J. Kim and B. T. Cho, "A New Approach to the Synthesis of Optically Active Norephedrine, Norpseudoephedrine and Cathinone via Double Asymmetric Induction," Bulletin of the Korean Chemical Society, vol. 24, no. 11, pp. 1641-0, 2003. DOI: 10.5012/bkcs.2003.24.11.1641.

[ACM Style]

Dong Jun Kim and Byung Tae Cho. 2003. A New Approach to the Synthesis of Optically Active Norephedrine, Norpseudoephedrine and Cathinone via Double Asymmetric Induction. Bulletin of the Korean Chemical Society, 24, 11, (2003), 1641-0. DOI: 10.5012/bkcs.2003.24.11.1641.

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ISSN(Print) 0253-2964
ISSN(Online) 1229-5949