Biological Activities of Methyl-4-[[(2E)-3,7-dimethyl-oxy]-3-hydroxybenzoate 


Vol. 25,  No. 2, pp. 195-197, Feb.  2004
10.5012/bkcs.2004.25.2.195


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  Abstract

Methyl-4-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-3-hydroxybenzoate (5) has been identified from the New Zealand liverwort Trichocolea hatcheri (T. hatcheri) on the basis of spectroscopic evidence. This compound was tested for its growth inhibitory effects against tumor cell lines, using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. It showed growth inhibition activity against Staphylococcus epidermidis (MIC, 1,000 μg/mL). These results suggest that compound 5 possesses antitumoral , antimicrobial and antioxidative activities.

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  Cite this article

[IEEE Style]

S. H. Baek, H. J. Oh, J. A. Lim, H. J. Chun, H. O. Lee, J. W. Ahn, N. B. Perry, H. M. Kim, "Biological Activities of Methyl-4-[[(2E)-3,7-dimethyl-oxy]-3-hydroxybenzoate," Bulletin of the Korean Chemical Society, vol. 25, no. 2, pp. 195-197, 2004. DOI: 10.5012/bkcs.2004.25.2.195.

[ACM Style]

Seung Hwa Baek, Hyun Ju Oh, Jin A Lim, Hyun Ja Chun, Hyun Ok Lee, Jong Woong Ahn, Nigel B Perry, and Hyung Min Kim. 2004. Biological Activities of Methyl-4-[[(2E)-3,7-dimethyl-oxy]-3-hydroxybenzoate. Bulletin of the Korean Chemical Society, 25, 2, (2004), 195-197. DOI: 10.5012/bkcs.2004.25.2.195.

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ISSN(Print) 0253-2964
ISSN(Online) 1229-5949