Design and Synthesis of a Cyclopentene Scaffold Mimicking Oseltamivir as a Novel Neuraminidase Inhibitor 


Vol. 29,  No. 11, pp. 2221-0, Nov.  2008
10.5012/bkcs.2008.29.11.2221


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  Abstract

The first synthesis of a cyclopentene version of oseltamivir as a novel neuraminidase inhibitor was achieved via the key cyclopentenone intermediate 4, which was prepared via syn-elimination from ketone derivative 2.

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  Cite this article

[IEEE Style]

F. Piao and J. H. Hong, "Design and Synthesis of a Cyclopentene Scaffold Mimicking Oseltamivir as a Novel Neuraminidase Inhibitor," Bulletin of the Korean Chemical Society, vol. 29, no. 11, pp. 2221-0, 2008. DOI: 10.5012/bkcs.2008.29.11.2221.

[ACM Style]

Fushan Piao and Joon Hee Hong. 2008. Design and Synthesis of a Cyclopentene Scaffold Mimicking Oseltamivir as a Novel Neuraminidase Inhibitor. Bulletin of the Korean Chemical Society, 29, 11, (2008), 2221-0. DOI: 10.5012/bkcs.2008.29.11.2221.