Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies 


Vol. 33,  No. 10, pp. 3191-3195, Oct.  2012
10.5012/bkcs.2012.33.10.3191


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  Abstract

New silver nanoparticle (AgNP)-loaded amino acid based hydrogels were synthesized successfully from poly (vinyl alcohol) (PVA) and poly(acryl amide-co-acryloyl phenyl alanine) (PAA) by redox polymerization. The formation of AgNP in hydrogels was confirmed by using a UV-Vis spectrophotometer and XRD. The structure and morphology of silver nanocomposite hydrogels were studied by using a scanning electron microscopy (SEM), which demonstrated scattered nanoparticles, ca. 10-20 nm. Thermogravimetric analysis revealed large differences of weight loss (i.e., 48%) between the prestine hydrogel and silver nanocomposite. The antibacterial studies of AgNP-loaded PAA (Ag-PAA) hydrogels was evaluated against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) bacteria. These Ag-PAA hydrogels showed significant activities against all the test bacteria. Newly developed hydrogels could be used for medical applications, such as artificial burn dressings.

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  Cite this article

[IEEE Style]

H. Cha, V. R. Babu, K. S. V. K. Rao, Y. Kim, S. Mei, W. H. Joo, Y. Lee, "Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies," Bulletin of the Korean Chemical Society, vol. 33, no. 10, pp. 3191-3195, 2012. DOI: 10.5012/bkcs.2012.33.10.3191.

[ACM Style]

Hyeong-Rae Cha, V. Ramesh Babu, K. S. V. Krishna Rao, Yong-Hyun Kim, Surong Mei, Woo Hong Joo, and Yong-Ill Lee. 2012. Fabrication of Amino Acid Based Silver Nanocomposite Hydrogels from PVA- Poly(Acrylamide-co-Acryloyl phenylalanine) and Their Antimicrobial Studies. Bulletin of the Korean Chemical Society, 33, 10, (2012), 3191-3195. DOI: 10.5012/bkcs.2012.33.10.3191.

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ISSN(Print) 0253-2964
ISSN(Online) 1229-5949