An Efficient Synthesis of Substituted Furans by Cupric Halide-Mediated Intramolecular Halocyclization of 2-(1-Alkynyl)-2-alken-1-ones 


Vol. 34,  No. 3, pp. 887-891, Mar.  2013
10.5012/bkcs.2013.34.3.887


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  Abstract

An efficient synthesis of 3-halofurans by the intramolecular cyclization of 2-(1-alkynyl)-2-alken-1-ones with cupric halide has been developed. A broad range of 3-chloro- and 3-bromofuran derivatives could be obtained in the present method in moderate to good yields. The 3-halofuran derivatives are potential synthetic intermediates for amplification of molecular complexity.

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  Cite this article

[IEEE Style]

W. Fu, F. Xu, W. Guo, M. Zhu, C. Xu, "An Efficient Synthesis of Substituted Furans by Cupric Halide-Mediated Intramolecular Halocyclization of 2-(1-Alkynyl)-2-alken-1-ones," Bulletin of the Korean Chemical Society, vol. 34, no. 3, pp. 887-891, 2013. DOI: 10.5012/bkcs.2013.34.3.887.

[ACM Style]

Wei-jun Fu, Feng-juan Xu, Wen-bo Guo, Mei Zhu, and Chen Xu. 2013. An Efficient Synthesis of Substituted Furans by Cupric Halide-Mediated Intramolecular Halocyclization of 2-(1-Alkynyl)-2-alken-1-ones. Bulletin of the Korean Chemical Society, 34, 3, (2013), 887-891. DOI: 10.5012/bkcs.2013.34.3.887.

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ISSN(Print) 0253-2964
ISSN(Online) 1229-5949