Facile Synthetic Routes to Prepare α-Muricholic Acid, Hyocholic Acid, and Their Taurine Conjugates 


Vol. 34,  No. 8, pp. 2436-2440, Aug.  2013
10.5012/bkcs.2013.34.8.2436


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  Abstract

α-Muricholic acid was synthesized through 9 steps from chenodeoxycholic acid with 26% overall yield. Hyocholic acid was synthesized through 8 steps from the same starting material with 63% overall yield. Taurine conjugates of α-muricholic acid and hyocholic acid were also prepared via their pentafluorophenyl ester.

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[IEEE Style]

D. W. Kang and H. F. Luecke, "Facile Synthetic Routes to Prepare α-Muricholic Acid, Hyocholic Acid, and Their Taurine Conjugates," Bulletin of the Korean Chemical Society, vol. 34, no. 8, pp. 2436-2440, 2013. DOI: 10.5012/bkcs.2013.34.8.2436.

[ACM Style]

Dong Wook Kang and Hans F. Luecke. 2013. Facile Synthetic Routes to Prepare α-Muricholic Acid, Hyocholic Acid, and Their Taurine Conjugates. Bulletin of the Korean Chemical Society, 34, 8, (2013), 2436-2440. DOI: 10.5012/bkcs.2013.34.8.2436.

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ISSN(Print) 0253-2964
ISSN(Online) 1229-5949