Entry to Highly Hindered Chiral β-Amino Triazoles Bearing a gem-Diaryl Group by Azide-alkyne Click Chemistry 


Vol. 35,  No. 6, pp. 1605-1612, Jun.  2014
10.5012/bkcs.2014.35.6.1605


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  Abstract

Copper(I)-catalyzed Huisgen cycloaddition of terminal alkynes with unmasked azidoamines derived from amino acids is described. The reported strategy provides a new entry to highly hindered β-amino 1,2,3-triazole derivatives bearing a gem-diaryl group, which are potentially valuable entities as molecular catalysts for asymmetric transformations.

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  Cite this article

[IEEE Style]

V. S. Sadu, H. N. Roy, P. Arigala, I. Hwang, K. Lee, "Entry to Highly Hindered Chiral β-Amino Triazoles Bearing a gem-Diaryl Group by Azide-alkyne Click Chemistry," Bulletin of the Korean Chemical Society, vol. 35, no. 6, pp. 1605-1612, 2014. DOI: 10.5012/bkcs.2014.35.6.1605.

[ACM Style]

Venkata Subbaiah Sadu, Harendra Nath Roy, Pitchaiah Arigala, In-Taek Hwang, and Kee-In Lee. 2014. Entry to Highly Hindered Chiral β-Amino Triazoles Bearing a gem-Diaryl Group by Azide-alkyne Click Chemistry. Bulletin of the Korean Chemical Society, 35, 6, (2014), 1605-1612. DOI: 10.5012/bkcs.2014.35.6.1605.